PROGRAM

PRELIMINARY PROGRAM

THURSDAY, SEPTEMBER 18

Presentation

15:30 Presentation (Conselleiro de Sanidade, Gerencia del CHUAC, Eduardo Villacorta, José Manuel Vázquez Rodríguez)
15:45 Welcome to Hypertrophic Cardiomyopathy in A Coruña. William J. Mckenna and Roberto Barriales-Villa

15:50-16:45 Genetic basis of HCM on 2025

Moderators: Philip Charron, James Ware
15:50-15:55 Clinical case (5 minutes) María Valverde
15:55-16:05 Is PRS in HCM ready for the primetime? (10 minutes) Connie Bezzina
16:05-16:15 Between a rock and a hard place: intermediate effect variants and semi-dominance in HCM (10 minutes) Juan P. Ochoa
16:15: 16:25 Familial HCM with negative NGS: what is the next step? (10 minutes) Jodie Ingles
16:25 -16:45 Panel discussion (20 minutes) Speakers and Luis Lopes

16:45-17:35 Gene therapy in HCM (joint session with industry)

Moderators: Jodie Ingles, Eva Van Rooij
16:45-16:55 Tenaya Therapeutics (MyPeak-1 Phase 1b clinical trial) (10 minutes) Natalia Paterson-Sonicheva
16:55-17:05 Lexeo Therapeutics (Gene Therapy for Cardiomyopathy Associated with Friedreich’s Ataxia) (10 minutes) Gregory Aubert
17:05-17:15 Rocket Pharma (A gene therapy study of RP-A501 in male patients with Danon disease) (10 minutes) TBD
17:15-17:35 Panel discussion (20 minutes) Speakers, Juan P. Kaski and Perry Elliott

17:35- 18:10 Coffee break (Poster Exhibition)

18:10-19:05 Cardiac Myosin Inhibitors: an evolving story

Moderators: Albert Hagege, Nuno Cardim
18:10-18:15 Clinical case (5 minutes) Fernando Dominguez
18:15-18:25 CMI in obstructive HCM (10 minutes) Iacopo Olivotto
18:25-18:35 CMI in non-obstructive HCM (10 minutes) Anjali Owens
18:35-18:45 Factors that influences the response to CMI (10 minutes) Ahmad Masri
18:45-19:05 Panel discussion (20 minutes) Speakers and Michele Michelis

19:05-19:50 Invasive septal reduction therapies in 2025?

Moderators: Maite Tomé and Luis Ruiz-Guerrero
19:05-19:10 Clinical case (5 minutes) Ana García
19:10-19:20 New surgical myectomy techniques: when to do? (10 minutes) Eduard Quintana
19:20-19:30 New catheter-based interventions in HCM (10 minutes) Jorge Sánz-Sánchez
19:30: 19:50 Panel discussion (20 minutes) Speakers, Hubert Seggewiss and JM García Pinilla

19:50 End of the day

FRIDAY, SEPTEMBER 19

9:00-9:55 New oral treatments in HCM (joint session with industry)

Moderators: Juan R. Gimeno, Esther Zorio
9:05-9:15 Edgewise Therapeutics (EDG-7500 in HCM, CIRRUS-HCM trial) (10 minutes) Marc Semigran
9:15 -9: 25 Imbria Pharmaceuticals (Ninerafaxtat in non obstructive HCM; FORTITUDE-HCM) (10 minutes) TBD
9:25-9:35 Lexicon Pharmaceuticals (Sotaglifozin in HCM, SONATA-HCM trial) (10 minutes) TBD
09:35-9:55 Panel discussion (20 minutes) Speakers and Martin Maron

9:55 Controversies in Hypertrophic Cardiomyopathy risk stratification

Moderators: Rodríguez-Palomares, Anjali Owens,
9:55-10:00 Clinical case (5 minutes) María Angeles Espinosa-Castro
10:00-10:15 AHA/ACC criteria are more precise (15 minutes) Martin Maron
10:15-10:30 ESC criteria are enough (15 minutes) Perry Elliott
10:30-10:50 Panel discussion (20 minutes) Speakers, Lorenzo Monserrat and Iacopo Olivotto

10:50- 11-30 Coffee (Poster exhibition)

11:30 Exercise in Hypertrophic Cardiomyopathy

Moderators: María L. Peña-Peña, Juan P. Kaski
11:30-11:35 Clinical case (5 minutes) Cayetana Barbeito-Caamaño
11:35-11:45 Exercise in HCM patients: when to say no (10 minutes) María Sanz
11:45-11:55 Potencial value of CPET in HCM (10 minutes) Caroline Coats
11:55-12:10 Panel discussion (15 minutes) Speakers, Juan R. Gimeno and Eduardo Villacorta

12:15 Atrial Fibrillation in Hypertrophic Cardiomyopathy

Moderators: William Mckenna, Larrañaga-Moreira
12:20-12:25 Clinical case (5 minutes) Jorge Garrido
12:25-12:35 Challenges in the medical management of atrial fibrillation (10 minutes) Elena Arbelo
12:35-12:45 Challenges in the interventional management of atrial fibrillation (10 minutes) Juan Jiménez-Jaimez
12:45-13:00 Panel discussion (15 minutes) Speakers, M. Michelis and Albert Hagege

13:00-13:20 Keynote Lecture

13:20-14:30 Cocktail Lunch (Poster Exhibition)

14:35-15:30 ATTR Amyloidosis: treatment update

15:35 Controversies in Fabry Disease

Moderators: Olga Azevedo, Javier Limeres
15:35-15:40 Clinical case (5 minutes) María Luisa Peña-Peña
15:40-15:50 Substrate reduction and gene therapy in Fabry disease (10 minutes) Maurizio Pieroni
15:50-16:00 Does immunogenicity play a role in the patient’s treatment? (10 minutes) Juan Politei
16:00:16:10 When to start treatment in woman? (10 minutes) Alberto Ortiz
16:10-16:30 Panel discussion (20 minutes) Speakers and Elena Biagini

16:30 Award Ceremony for the best poster

17:00 Closing